Positioned strategically throughout the central nervous system (CNS), in the meninges, choroid plexus, perivascular spaces, and even adjacent to neurons, mast cells maintain close contact with neurons, glia, and endothelial cells
This is significantly less expensive than pharmaceutical-grade products, which can cost $1,000 to $1,500 per month without insurance
For these reasons, it can be worth the extra effort to clone an expression construct for a GST-fusion form of your protein of interest if youre searching for interacting proteins
It also notes that in one cited human study, 20 mg per day for 3 months was associated with lower LDL cholesterol versus placebo